SGLT2阻害薬 クレアチニンクリアランス≧60ml/min
|
Canagliflozin
(Invokana) |
Dapagliflozin
(Forxiga) |
Empagliflozin
(Jardiance) |
|
100mg
or 300mg OD
|
10mg
OD
|
10mg
or 25mg OD
|
DPP4阻害薬 クレアチニンクリアランス≧50ml/min
|
Alogliptin
(Nesina)
|
Linagliptin
(Trajenta) |
Saxagliptin
(Onglyza) |
Sitagliptin
(Januvia) |
Vildagliptin
(Galvus) |
|
25mg
OD
|
5mg
OD
|
2.5mg
or 5mg OD
|
100mg
OD
|
50mg
OD or BD
|
シンガポールのDM治療経口薬 太字は政府の補助金対象の薬
|
Biguanides
|
Metformin
|
|
|
Sulfonylureas
|
Gliclazide
Glimepiride
(Amaryl)
Glipizide
Tolbutamide
|
Glimepiride + MET (Amaryl M) |
|
SGLT-2
inhibitors
|
Canagliflozin
(Invokana) Dapagliflozin (Forxiga) Empagliflozin
(Jardiance)
|
Dapagliflozin + MET (Xigduo XR) Empagliflozin + MET (Jardiance Duo) |
|
DPP-4
inhibitors
|
Alogliptin
(Nesina)
Linagliptin (Trajenta) Saxagliptin (Onglyza) Sitagliptin (Januvia) Vildagliptin (Galvus) |
Alogliptin
+ pioglitazone (Oseni)
Linagliptin + MET (Trajenta Duo) Saxagliptin + MET (Kombiglyze XR) Sitagliptin + MET (Janumet, Janumet XR) Vildagliptin + MET (Galvus Met) |
|
Meglitinides
|
Nateglinide
(Starlix) Repaglinide (Novonorm)
|
|
|
Thiazolidinediones
|
Pioglitazone
(Actos) Rosiglitazone (Avandia)
|
Alogliptin
+ pioglitazone (Oseni)
|
|
Alpha-glucosidase
inhibitors
|
Acarbose
(Glucobay)
|
|
参考文献